IL-4Ra blockade reduces influenza-associated morbidity in a murine model of allergic asthma
- Creator: Shahangian, Kimia , Ngan, David A. , Chen, H. H. Rachel , Oh, Yeni , Tam, Anthony , Wen, Jing , Cheung, Chung , Knight, Darryl A. , Dorscheid, Delbert R. , Hackett, Tillie L. , Hughes, Michael R. , McNagny, Kelly M. , Hirota, Jeremy A. , Niikura, Masahiro , Man, S. F. Paul , Sin, Don D.
- Resource Type: journal article
- Date: 2021
Animal models of COPD: what do they tell us?
- Creator: Jones, Bernadette , Donovan, Chantal , Hansbro, Philip M. , Liu, Gang , Gomez, Henry M. , Chimankar, Vrushali , Harrison, Celese L. , Wiegman, Cornelis H. , Adcock, Ian M. , Knight, Darryl A. , Hirota, Jeremy A.
- Resource Type: journal article
- Date: 2017
Attenuating immune pathology using a microbial-based intervention in a mouse model of cigarette smoke-induced lung inflammation
- Creator: Bazett, Mark , Biala, Agnieszka , Huff, Ryan D. , Zeglinksi, Matthew R. , Hansbro, Philip M. , Bosiljcic, Momir , Gunn, Hal , Kalyan, Shirin , Hirota, Jeremy A.
- Resource Type: journal article
- Date: 2017
Inflammasomes in the lung
- Creator: Pinkerton, James W. , Kim, Richard Y. , Robertson, Avril A. B. , Hirota, Jeremy A. , Wood, Lisa G. , Knight, Darryl A. , Cooper, Matthew A. , O'Neill, Luke A. J. , Horvat, Jay C. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2017
Mechanisms and treatments for severe, steroid-resistant allergic airway disease and asthma
- Creator: Hansbro, Philip M. , Kim, Richard Y. , Hirota, Jeremy A. , Knight, Darryl A. , Foster, Paul S. , Horvat, Jay C. , Starkey, Malcolm R. , Donovan, Chantal , Dua, Kamal , Mayall, Jemma R. , Liu, Gang , Hansbro, Nicole G. , Simpson, Jodie L. , Wood, Lisa G.
- Resource Type: journal article
- Date: 2017
Regulation of xanthine dehydrogensase gene expression and uric acid production in human airway epithelial cells
- Creator: Huff, Ryan D. , Hsu, Alan C.-Y. , Nichol, Kristy S. , Jones, Bernadette , Knight, Darryl A. , Wark, Peter A. B. , Hansbro, Philip M. , Hirota, Jeremy A.
- Resource Type: journal article
- Date: 2017
Role for NLRP3 inflammasome-mediated, IL-1ß-dependent responses in severe, steroid-resistant asthma
- Creator: Kim, Richard Y. , Pinkerton, James W. , Hirota, Jeremy A. , Wood, Lisa G. , Simpson, Jodie L. , Knight, Darryl A. , Wark, Peter A. , Gibson, Peter G. , O'Neill, Luke A. J. , Cooper, Matthew A. , Horvat, Jay C. , Hansbro, Philip M. , Essilfie, Ama T. , Robertson, Avril A. B. , Baines, Katherine J. , Brown, Alexandra C. , Mayall, Jemma R. , Ali, M. Khadem , Starkey, Malcolm R. , Hansbro, Nicole G.
- Resource Type: journal article
- Date: 2017
Disruption of ß-catenin/CBP signaling inhibits human airway epithelial-mesenchymal transition and repair
- Creator: Moheimani, Fatemeh , Roth, Hollis M. , Stick, Stephen M. , Hansbro, Philip M. , Hackett, Tillie-Louise , Knight, Darryl A. , Cross, Jennifer , Reid, Andrew T. , Shaheen, Furquan , Warner, Stephanie M. , Hirota, Jeremy A. , Kicic, Anthony , Hallstrand, Teal S. , Kahn, Michael
- Resource Type: journal article
- Date: 2015
The nucleotide-binding domain, leucine-rich repeat protein 3 inflammasome/IL-1 receptor I axis mediates innate, but not adaptive, immune responses after exposure to particulate matter under 10 µm
- Creator: Hirota, Jeremy A. , Gold, Matthew J. , McNagny, Kelly M. , Knight, Darryl A. , Hiebert, Paul R. , Parkinson, Leigh G. , Wee, Tracee , Smith, Dirk , Hansbro, Phil M. , Carlsten, Chris , VanEeden, Stephen , Sin, Don D.
- Resource Type: journal article
- Date: 2015
Urban particulate matter increases human airway epithelial cell IL-1β secretion following scratch wounding and H1N1 influenza A exposure in vitro
- Creator: Hirota, Jeremy A. , Marchant, David J. , Singhera, Gurpreet K. , Moheimani, Fatemeh , Dorscheid, Delbert R. , Carlsten, Christopher , Sin, Don , Knight, Darryl
- Resource Type: journal article
- Date: 2015
PM10-stimulated airway epithelial cells activate primary human dendritic cells independent of uric acid: application of an in vitro model system exposing dendritic cells to airway epithelial cell-conditioned media
- Creator: Hirota, Jeremy A. , Alexis, Neil E. , Pui, Mandy , Wong, SzeWing , Fung, Elkie , Hansbro, Phillip , Knight, Darryl , Sin, Don D. , Carlsten, Chris
- Resource Type: journal article
- Date: 2014
Granzyme B deficiency exacerbates lung inflammation in mice after acute lung injury
- Creator: Hirota, Jeremy A. , Hiebert, Paul R. , Gold, Matt , Wu, Dan , Graydon, Colin , Smith, Jane Ann , Ask, Kjetil , McNagny, Kelly , Granville, David J. , Knight, Darryl A.
- Resource Type: journal article
- Date: 2013